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Oat sensitivity
Oat sensitivity represents a sensitivity to the proteins found in oats, ''Avena sativa''. Sensitivity to oats
as a result of allergy or to the seed storage proteins either inhaled or ingested. A more complex condition results to individuals who have gluten-sensitive enteropathy in which there is also a response to avenin, the glutinous protein in oats similar to the gluten within wheat.
==Oat allergy==
Studies on farmers with grain dust allergy and children with atopy dermatitis reveal that oat proteins can act as both respiratory and skin allergens. Oat-dust sensitivity in farms found 53% showed reactivity to dust second only to barley (70%) and almost double that of wheat dust. The 66 kDa protein in oats was visualized by 28 out of 33 sera (84%), however, there was evident non-specific binding to this region and thus it may also represent lectin-like binding. However, IgA and IgG responses, like those seen to anti-gliadin antibodies in celiac disease or dermatitis herpetiformis, are not seen to avenins in atopic dermatitis patients. Food allergies to oats can accompany atopy dermatitis. Oat avenins share similarities with γ and ω-gliadins of wheat, based on these similarities they could potentiate both enteropathic response and anaphylactic responses. Oat allergy in gluten-sensitive enteropathy can explain an avenin sensitive individual who no histological abnormality, no T-cell reaction to avenin, bore the rarer DQ2.5''trans'' phenotype and had anaphylactic reaction to avenin.
''and Wheat dependent exercise-induced anaphylaxis''
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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